TY - JOUR
T1 - Trasplante de páncreas
T2 - ¿una solución para la diabetes tipo 1?
AU - Pulla, Daniela Alexandra Quinde
AU - Cabrera, Ana Belén Urgilés
AU - Heredia, Manuel Antonio Fajardo
AU - Lcdo, Roberto Carlos Durán Gutiérrez
AU - Vega, Andrei Mauricio Reyes
AU - Cruz, Wilson Marcelo Siguencia
N1 - Publisher Copyright:
© 2022, Venezuelan Society of Pharmacology and Clinical and Therapeutic Pharmacology. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Type 1 diabetes, although not as prevalent as type 2 diabetes, is also a disease in growth with repercussions in public health. Treatment typically concentrates in substituting the lack of insulin with exogenous injections and constant monitoring due to the risk of hypoglycemia; the fact that this condition is most prevalent in pediatric individuals only further hinders adherence to treatment. Thus, pancreatic transplant has emerged as a possible solution to the problems of insulin therapy. Although not all subjects are candidates for this procedure, those who qualify tend to greatly benefit from the procedure. Glycemic profiles and quality of life tend to improve significantly after the procedure. Those who do not qualify may instead benefit from an islet transplant. In general, the techniques of these procedures must remain under study so that they become more routinely and less extraordinary, with the intention of providing improved quality of life to patients. The objective of this review is to evaluate the different options within the concept of pancreas transplant, with their respective indications and complications.
AB - Type 1 diabetes, although not as prevalent as type 2 diabetes, is also a disease in growth with repercussions in public health. Treatment typically concentrates in substituting the lack of insulin with exogenous injections and constant monitoring due to the risk of hypoglycemia; the fact that this condition is most prevalent in pediatric individuals only further hinders adherence to treatment. Thus, pancreatic transplant has emerged as a possible solution to the problems of insulin therapy. Although not all subjects are candidates for this procedure, those who qualify tend to greatly benefit from the procedure. Glycemic profiles and quality of life tend to improve significantly after the procedure. Those who do not qualify may instead benefit from an islet transplant. In general, the techniques of these procedures must remain under study so that they become more routinely and less extraordinary, with the intention of providing improved quality of life to patients. The objective of this review is to evaluate the different options within the concept of pancreas transplant, with their respective indications and complications.
KW - glycemic control
KW - insulin therapy
KW - pancreas transplant
KW - pancreatic islet transplant
KW - Type 1 diabetes mellitus
UR - https://www.scopus.com/pages/publications/85146574098
U2 - 10.5281/zenodo.7410439
DO - 10.5281/zenodo.7410439
M3 - Artículo
AN - SCOPUS:85146574098
SN - 1856-4550
VL - 17
SP - 427
EP - 430
JO - Revista Latinoamericana de Hipertension
JF - Revista Latinoamericana de Hipertension
IS - 6
ER -