TY - JOUR
T1 - Plants and natural products with activity against various types of coronaviruses
T2 - A review with focus on sars‐cov‐2
AU - Llivisaca‐contreras, Susana A.
AU - Naranjo‐morán, Jaime
AU - Pino‐acosta, Andrea
AU - Pieters, Luc
AU - Vanden Berghe, Wim
AU - Manzano, Patricia
AU - Vargas‐pérez, Jeffrey
AU - León‐tamariz, Fabian
AU - Cevallos‐cevallos, Juan M.
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/7/1
Y1 - 2021/7/1
N2 - COVID‐19 is a pandemic disease caused by the SARS‐CoV‐2 virus, which is potentially fatal for vulnerable individuals. Disease management represents a challenge for many countries, given the shortage of medicines and hospital resources. The objective of this work was to review the medicinal plants, foods and natural products showing scientific evidence for host protection against various types of coronaviruses, with a focus on SARS‐CoV‐2. Natural products that mitigate the symptoms caused by various coronaviruses are also presented. Particular attention was placed on natural products that stabilize the Renin–Angiotensin–Aldosterone System (RAAS), which has been associated with the entry of the SARS‐CoV‐2 into human cells.
AB - COVID‐19 is a pandemic disease caused by the SARS‐CoV‐2 virus, which is potentially fatal for vulnerable individuals. Disease management represents a challenge for many countries, given the shortage of medicines and hospital resources. The objective of this work was to review the medicinal plants, foods and natural products showing scientific evidence for host protection against various types of coronaviruses, with a focus on SARS‐CoV‐2. Natural products that mitigate the symptoms caused by various coronaviruses are also presented. Particular attention was placed on natural products that stabilize the Renin–Angiotensin–Aldosterone System (RAAS), which has been associated with the entry of the SARS‐CoV‐2 into human cells.
KW - Angiotensin‐converting enzyme inhibitors (ACEi)
KW - Antiviral
KW - Biomolecules
KW - Coronavirus disease of 2019 (COVID‐19)
KW - Medicinal plants
KW - Middle east respiratory syndrome (MERS)
KW - Renin–angiotensin–aldosterone system (RAAS)
KW - Severe acute respiratory syndrome coronavirus (SARS‐CoV)
KW - Viral entry inhibitors
UR - https://www.scopus.com/pages/publications/85110399463
U2 - 10.3390/molecules26134099
DO - 10.3390/molecules26134099
M3 - Artículo de revisión
C2 - 34279439
AN - SCOPUS:85110399463
SN - 1420-3049
VL - 26
JO - Molecules
JF - Molecules
IS - 13
M1 - 4099
ER -
