TY - JOUR
T1 - Maternal Supplementation with Polyphenols and Omega-3 Fatty Acids during Pregnancy
T2 - Prenatal Effects on Fetal Fatty Acid Composition in the Iberian Pig
AU - Heras-Molina, Ana
AU - Escudero, Rosa
AU - Pesántez-Pacheco, José L.
AU - García-Contreras, Consolación
AU - Vázquez-Gómez, Marta
AU - Astiz, Susana
AU - Óvilo, Cristina
AU - González-Bulnes, Antonio
AU - Isabel, Beatriz
N1 - Publisher Copyright:
© 2022 by the authors.
PY - 2022/8
Y1 - 2022/8
N2 - Intrauterine Growth Restriction (IUGR) is a major problem in pig production and different strategies, mainly maternal supplementation with different agents, are currently being studied. The combination of hydroxytyrosol and n3-PUFA seems to be a promising treatment to counteract IUGR, since the combination may help improve n3-PUFA composition and lower the inflammatory status of IUGR piglets. The aim of the present study is to determine the effects of a maternal supplementation, from day 35 to day 100 of pregnancy, with linseed oil and hydroxytyrosol on the fetal FA composition. The results showed higher n3 levels, including eicosapentaenoic and docosahexaenoic FA in the offspring from treated gilts, which showed lower n6-PUFA/n3-PUFA (n6/n3) ratios. Saturated and monounsaturated fatty acids were also affected by treatment, especially in the muscle and brain. Thus, a maternal supplementation with linseed oil and hydroxytyrosol affected the fetal FA tissue composition, which could have implications in pig production due to the improvement of the piglets’ health status.
AB - Intrauterine Growth Restriction (IUGR) is a major problem in pig production and different strategies, mainly maternal supplementation with different agents, are currently being studied. The combination of hydroxytyrosol and n3-PUFA seems to be a promising treatment to counteract IUGR, since the combination may help improve n3-PUFA composition and lower the inflammatory status of IUGR piglets. The aim of the present study is to determine the effects of a maternal supplementation, from day 35 to day 100 of pregnancy, with linseed oil and hydroxytyrosol on the fetal FA composition. The results showed higher n3 levels, including eicosapentaenoic and docosahexaenoic FA in the offspring from treated gilts, which showed lower n6-PUFA/n3-PUFA (n6/n3) ratios. Saturated and monounsaturated fatty acids were also affected by treatment, especially in the muscle and brain. Thus, a maternal supplementation with linseed oil and hydroxytyrosol affected the fetal FA tissue composition, which could have implications in pig production due to the improvement of the piglets’ health status.
KW - hydroxytyrosol
KW - linseed oil
KW - progeny
KW - swine
UR - https://www.scopus.com/pages/publications/85137321382
U2 - 10.3390/ani12162140
DO - 10.3390/ani12162140
M3 - Artículo
AN - SCOPUS:85137321382
SN - 2076-2615
VL - 12
JO - Animals
JF - Animals
IS - 16
M1 - 2140
ER -