Fabrication of 3D bioactive ceramic scaffolds by robocasting

S. Andrade, A. Abdalla, E. Montufar, L. Corté, P. Vanegas

Producción científica: Capítulo del libro/informe/acta de congresoContribución a la conferenciarevisión exhaustiva

1 Cita (Scopus)

Resumen

Tricalcium phosphate ceramics are bioactive and osteoconductive biomaterials that support cellular functions and can develop appropriate mechanical characteristics for bone tissue engineering. Fast prototyping techniques permit to obtain accurate control over scaffolding architecture with high reproducibility. Flexible composites are considered to promote mechano-biological stimulation during cell culture. The aim of this study is to fabricate flexible bioceramic scaffolds by robocasting and to determine biological improvements related to their added flexible properties. Characterized 3D β - TCP/gelatin scaffolds with interconnected porous structure were fabricated using robocasting. SEM micrographs showed fabricated porous scaffolds with desired pore size (~200 μm), rods diameter (~840 μm), porosity and mechanical strength. Alamar Blue assay was performed for static and dynamic cultures along 21 days. Oscillatory flow conditions allowed considerable higher cell proliferation compared with static conditions.

Idioma originalInglés
Título de la publicación alojadaVI Latin American Congress on Biomedical Engineering, CLAIB 2014
EditoresAriel Braidot, Alejandro Hadad
EditorialSpringer Verlag
Páginas167-169
Número de páginas3
ISBN (versión digital)9783319131160
DOI
EstadoPublicada - 2015
Evento6th Latin American Congress on Biomedical Engineering, CLAIB 2014 - Paraná, Argentina
Duración: 29 oct. 201431 oct. 2014

Serie de la publicación

NombreIFMBE Proceedings
Volumen49
ISSN (versión impresa)1680-0737

Conferencia

Conferencia6th Latin American Congress on Biomedical Engineering, CLAIB 2014
País/TerritorioArgentina
CiudadParaná
Período29/10/1431/10/14

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