TY - JOUR
T1 - CD20, generalidades básicas-moleculares y su posible relación como marcador de mal pronóstico en leucemia
AU - Bastidas Sánchez, Andrea Natali
AU - Bigoni Ordonez, Gabriele Davide
PY - 2023/1/1
Y1 - 2023/1/1
N2 - CD20 is a transmembrane protein expressed on the surface of the B lymphocyte and plays a significant role in its development and differentiation. It is expressed in most B-cell neoplasms, such as Acute Lymphoblastic Leukemia (ALL). Information was collected on the biological and molecular structure of the CD20 marker and its regulation mechanism to improve the understanding of its function within the cell, the effect it exerts as a marker of poor prognosis when expressed in adult patients diagnosed with ALL, and the advantages of being used as a therapeutic target in this pathology.
AB - CD20 is a transmembrane protein expressed on the surface of the B lymphocyte and plays a significant role in its development and differentiation. It is expressed in most B-cell neoplasms, such as Acute Lymphoblastic Leukemia (ALL). Information was collected on the biological and molecular structure of the CD20 marker and its regulation mechanism to improve the understanding of its function within the cell, the effect it exerts as a marker of poor prognosis when expressed in adult patients diagnosed with ALL, and the advantages of being used as a therapeutic target in this pathology.
KW - CD20; Prognostic factor; Acute lymphoblastic leukemia; B lymphocyte
KW - CD20; Prognostic factor; Acute lymphoblastic leukemia; B lymphocyte
UR - https://editorial.ucuenca.edu.ec/omp/index.php/ucp/catalog/book/45#:~:text=No%20m%C3%A1s%20tinieblas%2C%20ser%C3%ADa%20el,y%20defender%20el%20pensamiento%20libre.
M3 - Artículo
JO - Revista Colombiana de Cancerología
JF - Revista Colombiana de Cancerología
ER -
