CARACTERIZACIÓN DE LOS GENOTIPOS FRECUENTES DEL VIRUS DEL PAPILOMA HUMANO EN MUJERES ATENDIDAS EN LOS HOSPITALES MONTE SINAI Y DEL SEGURO SOCIAL CUENCA- ECUADOR. 2008- 2014.

Manuel Alfredo Campoverde Cisneros, John Patricio Caguana Mayancela, Mauro Javier Arcentales Cayamcela

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

Resumen

OBJECTIVE: To determine the prevalence of hu- man papilloma virus genotypes in cervical-uterine samples and their relation to risk factors in women with active sex life in Cuenca. METHODOLOGY: It is a cross-sectional observatio- nal study with a sample of 500 women from Cuen- ca who were attended in the Monte Sinai Hospi- tal and the Ecuadorian Institute of Social Security (IESS). The exams were carried out in the BIONCO- GEN Molecular Biology Laboratory which is loca- ted in Cuenca. The Real Time PCR technique plus the Pap examination were used. RESULTS: The prevalence of HPV was 78.4 % and the most frequent genotype was the HPV 16 with 26.2 %. On the other hand, the CIN I with 27% is the most frequent gynecological pathology. CONCLUSION: The genotypes 16/18 represent the types of HPV that are directly related to the de- velopment of cervical cancer because when it is correlated with cytology (Pap) it is demonstrated that the cell undergoes morphological changes (koilocytosis).
Idioma originalEspañol
PublicaciónRevistade la Facultad de Ciencias Médicas
EstadoPublicada - 2017
Publicado de forma externa

Palabras clave

  • Genotipo; Papillomavirus Humano 16; Papillomavirus Humano 18; Técnicas de Labo- ratorio Clínico; PCR; Factores de riesgo; Hospital Monte Sinai; Hospital del Instituto Ecuatoriano de Seguridad Social; Cuenca-Ecuador

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