Resumen
OBJECTIVE: To determine the prevalence of hu-
man papilloma virus genotypes in cervical-uterine
samples and their relation to risk factors in women
with active sex life in Cuenca.
METHODOLOGY: It is a cross-sectional observatio-
nal study with a sample of 500 women from Cuen-
ca who were attended in the Monte Sinai Hospi-
tal and the Ecuadorian Institute of Social Security
(IESS). The exams were carried out in the BIONCO-
GEN Molecular Biology Laboratory which is loca-
ted in Cuenca. The Real Time PCR technique plus
the Pap examination were used.
RESULTS: The prevalence of HPV was 78.4 % and
the most frequent genotype was the HPV 16 with
26.2 %. On the other hand, the CIN I with 27% is the
most frequent gynecological pathology.
CONCLUSION: The genotypes 16/18 represent the
types of HPV that are directly related to the de-
velopment of cervical cancer because when it is
correlated with cytology (Pap) it is demonstrated
that the cell undergoes morphological changes
(koilocytosis).
| Idioma original | Español |
|---|---|
| Publicación | Revistade la Facultad de Ciencias Médicas |
| Estado | Publicada - 2017 |
| Publicado de forma externa | Sí |
Palabras clave
- Genotipo; Papillomavirus Humano 16; Papillomavirus Humano 18; Técnicas de Labo- ratorio Clínico; PCR; Factores de riesgo; Hospital Monte Sinai; Hospital del Instituto Ecuatoriano de Seguridad Social; Cuenca-Ecuador