A MCEM based multistate model of interval-censored and correlated panel data for neurocysticercosis study

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Resumen

We propose a multistate model to analyse interval-censored event-history data subject to within-unit clustering. The model is motivated by a study of the neurocysticercosis evolution at cyst-level, considering the multiple cysts phases within the brain at pre-scheduled imaging time points. Of interest is the study of the intra-brain distribution of the process leading to cyst resolution, and whether this distribution varies with the anthelmintic treatment. We develop a likelihood-based method using Monto Carlo EM algorithm for the inference. The practical utility of the methods is illustrated using data from a longitudinal study on albendazole's therapeutic effect among patients from six hospitals in Ecuador.

Idioma originalInglés
Título de la publicación alojada2nd International Conference on Statistics
Subtítulo de la publicación alojadaTheory and Applications, ICSTA 2020
EditoresGangaram S. Ladde, Noelle Samia
EditorialAvestia Publishing
ISBN (versión impresa)9781927877685
DOI
EstadoPublicada - 2020
Evento2nd International Conference on Statistics: Theory and Applications, ICSTA 2020 - Virtual, Online
Duración: 19 ago. 202021 ago. 2020

Serie de la publicación

NombreProceedings of the International Conference on Statistics
ISSN (versión digital)2562-7767

Conferencia

Conferencia2nd International Conference on Statistics: Theory and Applications, ICSTA 2020
CiudadVirtual, Online
Período19/08/2021/08/20

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