Plants and natural products with activity against various types of coronaviruses: A review with focus on sars‐cov‐2

Susana A. Llivisaca‐contreras; Jaime Naranjo‐morán; Andrea Pino‐acosta; Luc Pieters; Wim Vanden Berghe; Patricia Manzano; Jeffrey Vargas‐pérez; Fabian León‐tamariz; Juan M. Cevallos‐cevallos

doi:10.3390/molecules26134099

Plants and natural products with activity against various types of coronaviruses: A review with focus on sars‐cov‐2

Susana A. Llivisaca‐contreras (First Author)
, Jaime Naranjo‐morán
, Andrea Pino‐acosta
, Luc Pieters
, Wim Vanden Berghe
, Patricia Manzano
, Jeffrey Vargas‐pérez
, Fabian León‐tamariz
, Juan M. Cevallos‐cevallos (Last Author)

Escuela Superior Politécnica del Litoral
University of Antwerp
Red Universitaria Para la Investigación y Posgrados Vlir Network Ecuador

Research output: Contribution to journal › Review article › peer-review

37 Scopus citations

Abstract

COVID‐19 is a pandemic disease caused by the SARS‐CoV‐2 virus, which is potentially fatal for vulnerable individuals. Disease management represents a challenge for many countries, given the shortage of medicines and hospital resources. The objective of this work was to review the medicinal plants, foods and natural products showing scientific evidence for host protection against various types of coronaviruses, with a focus on SARS‐CoV‐2. Natural products that mitigate the symptoms caused by various coronaviruses are also presented. Particular attention was placed on natural products that stabilize the Renin–Angiotensin–Aldosterone System (RAAS), which has been associated with the entry of the SARS‐CoV‐2 into human cells.

Original language	English
Article number	4099
Journal	Molecules
Volume	26
Issue number	13
DOIs	https://doi.org/10.3390/molecules26134099
State	Published - 1 Jul 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Angiotensin‐converting enzyme inhibitors (ACEi)
Antiviral
Biomolecules
Coronavirus disease of 2019 (COVID‐19)
Medicinal plants
Middle east respiratory syndrome (MERS)
Renin–angiotensin–aldosterone system (RAAS)
Severe acute respiratory syndrome coronavirus (SARS‐CoV)
Viral entry inhibitors

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10.3390/molecules26134099

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Llivisaca‐contreras, S. A., Naranjo‐morán, J., Pino‐acosta, A., Pieters, L., Vanden Berghe, W., Manzano, P., Vargas‐pérez, J., León‐tamariz, F., & Cevallos‐cevallos, J. M. (2021). Plants and natural products with activity against various types of coronaviruses: A review with focus on sars‐cov‐2. Molecules, 26(13), Article 4099. https://doi.org/10.3390/molecules26134099

@article{9247a87211c94ad4be0965ee0a2ebd2a,

title = "Plants and natural products with activity against various types of coronaviruses: A review with focus on sars‐cov‐2",

abstract = "COVID‐19 is a pandemic disease caused by the SARS‐CoV‐2 virus, which is potentially fatal for vulnerable individuals. Disease management represents a challenge for many countries, given the shortage of medicines and hospital resources. The objective of this work was to review the medicinal plants, foods and natural products showing scientific evidence for host protection against various types of coronaviruses, with a focus on SARS‐CoV‐2. Natural products that mitigate the symptoms caused by various coronaviruses are also presented. Particular attention was placed on natural products that stabilize the Renin–Angiotensin–Aldosterone System (RAAS), which has been associated with the entry of the SARS‐CoV‐2 into human cells. ",

keywords = "Angiotensin‐converting enzyme inhibitors (ACEi), Antiviral, Biomolecules, Coronavirus disease of 2019 (COVID‐19), Medicinal plants, Middle east respiratory syndrome (MERS), Renin–angiotensin–aldosterone system (RAAS), Severe acute respiratory syndrome coronavirus (SARS‐CoV), Viral entry inhibitors",

author = "Llivisaca‐contreras, \{Susana A.\} and Jaime Naranjo‐mor{\'a}n and Andrea Pino‐acosta and Luc Pieters and \{Vanden Berghe\}, Wim and Patricia Manzano and Jeffrey Vargas‐p{\'e}rez and Fabian Le{\'o}n‐tamariz and Cevallos‐cevallos, \{Juan M.\}",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

month = jul,

day = "1",

doi = "10.3390/molecules26134099",

language = "Ingl{\'e}s",

volume = "26",

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Llivisaca‐contreras, SA, Naranjo‐morán, J, Pino‐acosta, A, Pieters, L, Vanden Berghe, W, Manzano, P, Vargas‐pérez, J, León‐tamariz, F & Cevallos‐cevallos, JM 2021, 'Plants and natural products with activity against various types of coronaviruses: A review with focus on sars‐cov‐2', Molecules, vol. 26, no. 13, 4099. https://doi.org/10.3390/molecules26134099

TY - JOUR

T1 - Plants and natural products with activity against various types of coronaviruses

T2 - A review with focus on sars‐cov‐2

AU - Llivisaca‐contreras, Susana A.

AU - Naranjo‐morán, Jaime

AU - Pino‐acosta, Andrea

AU - Pieters, Luc

AU - Vanden Berghe, Wim

AU - Manzano, Patricia

AU - Vargas‐pérez, Jeffrey

AU - León‐tamariz, Fabian

AU - Cevallos‐cevallos, Juan M.

PY - 2021/7/1

Y1 - 2021/7/1

N2 - COVID‐19 is a pandemic disease caused by the SARS‐CoV‐2 virus, which is potentially fatal for vulnerable individuals. Disease management represents a challenge for many countries, given the shortage of medicines and hospital resources. The objective of this work was to review the medicinal plants, foods and natural products showing scientific evidence for host protection against various types of coronaviruses, with a focus on SARS‐CoV‐2. Natural products that mitigate the symptoms caused by various coronaviruses are also presented. Particular attention was placed on natural products that stabilize the Renin–Angiotensin–Aldosterone System (RAAS), which has been associated with the entry of the SARS‐CoV‐2 into human cells.

AB - COVID‐19 is a pandemic disease caused by the SARS‐CoV‐2 virus, which is potentially fatal for vulnerable individuals. Disease management represents a challenge for many countries, given the shortage of medicines and hospital resources. The objective of this work was to review the medicinal plants, foods and natural products showing scientific evidence for host protection against various types of coronaviruses, with a focus on SARS‐CoV‐2. Natural products that mitigate the symptoms caused by various coronaviruses are also presented. Particular attention was placed on natural products that stabilize the Renin–Angiotensin–Aldosterone System (RAAS), which has been associated with the entry of the SARS‐CoV‐2 into human cells.

KW - Angiotensin‐converting enzyme inhibitors (ACEi)

KW - Antiviral

KW - Biomolecules

KW - Coronavirus disease of 2019 (COVID‐19)

KW - Medicinal plants

KW - Middle east respiratory syndrome (MERS)

KW - Renin–angiotensin–aldosterone system (RAAS)

KW - Severe acute respiratory syndrome coronavirus (SARS‐CoV)

KW - Viral entry inhibitors

UR - https://www.scopus.com/pages/publications/85110399463

U2 - 10.3390/molecules26134099

DO - 10.3390/molecules26134099

M3 - Artículo de revisión

C2 - 34279439

AN - SCOPUS:85110399463

SN - 1420-3049

VL - 26

JO - Molecules

JF - Molecules

IS - 13

M1 - 4099

ER -

Plants and natural products with activity against various types of coronaviruses: A review with focus on sars‐cov‐2

Abstract

UN SDGs

Keywords

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