CD20, generalidades básicas-moleculares y su posible relación como marcador de mal pronóstico en leucemia

Andrea Natali Bastidas Sánchez; Gabriele Davide Bigoni Ordonez

CD20, generalidades básicas-moleculares y su posible relación como marcador de mal pronóstico en leucemia

Andrea Natali Bastidas Sánchez (First Author)
, Gabriele Davide Bigoni Ordonez

Facultad de Ciencias Médicas

Research output: Contribution to journal › Article › peer-review

Abstract

CD20 is a transmembrane protein expressed on the surface of the B lymphocyte and plays a significant role in its development and differentiation. It is expressed in most B-cell neoplasms, such as Acute Lymphoblastic Leukemia (ALL). Information was collected on the biological and molecular structure of the CD20 marker and its regulation mechanism to improve the understanding of its function within the cell, the effect it exerts as a marker of poor prognosis when expressed in adult patients diagnosed with ALL, and the advantages of being used as a therapeutic target in this pathology.

Original language	Spanish
Journal	Revista Colombiana de Cancerología
State	Published - 1 Jan 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

CD20; Prognostic factor; Acute lymphoblastic leukemia; B lymphocyte

Cite this

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abstract = "CD20 is a transmembrane protein expressed on the surface of the B lymphocyte and plays a significant role in its development and differentiation. It is expressed in most B-cell neoplasms, such as Acute Lymphoblastic Leukemia (ALL). Information was collected on the biological and molecular structure of the CD20 marker and its regulation mechanism to improve the understanding of its function within the cell, the effect it exerts as a marker of poor prognosis when expressed in adult patients diagnosed with ALL, and the advantages of being used as a therapeutic target in this pathology.",

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AU - Bastidas Sánchez, Andrea Natali

AU - Bigoni Ordonez, Gabriele Davide

PY - 2023/1/1

Y1 - 2023/1/1

N2 - CD20 is a transmembrane protein expressed on the surface of the B lymphocyte and plays a significant role in its development and differentiation. It is expressed in most B-cell neoplasms, such as Acute Lymphoblastic Leukemia (ALL). Information was collected on the biological and molecular structure of the CD20 marker and its regulation mechanism to improve the understanding of its function within the cell, the effect it exerts as a marker of poor prognosis when expressed in adult patients diagnosed with ALL, and the advantages of being used as a therapeutic target in this pathology.

AB - CD20 is a transmembrane protein expressed on the surface of the B lymphocyte and plays a significant role in its development and differentiation. It is expressed in most B-cell neoplasms, such as Acute Lymphoblastic Leukemia (ALL). Information was collected on the biological and molecular structure of the CD20 marker and its regulation mechanism to improve the understanding of its function within the cell, the effect it exerts as a marker of poor prognosis when expressed in adult patients diagnosed with ALL, and the advantages of being used as a therapeutic target in this pathology.

KW - CD20; Prognostic factor; Acute lymphoblastic leukemia; B lymphocyte

UR - https://editorial.ucuenca.edu.ec/omp/index.php/ucp/catalog/book/45#:~:text=No%20m%C3%A1s%20tinieblas%2C%20ser%C3%ADa%20el,y%20defender%20el%20pensamiento%20libre.

M3 - Artículo

JO - Revista Colombiana de Cancerología

JF - Revista Colombiana de Cancerología

ER -

CD20, generalidades básicas-moleculares y su posible relación como marcador de mal pronóstico en leucemia

Abstract

UN SDGs

Keywords

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Cite this