Assessment of the anti-inflammatory activity of medicinal plants through the use of the biological model of zebra fish.

The project "Implementation of the Biological Model of Cebra Fish for study of anti-inflammatory activity of native medicinal plants of Ecuador" is intended to implement a state-of-the-art technological contribution to the research that has been carrying out the project of medicinal plants of the VLIR-IUC program of the University of Cuenca; This will allow the extension of the study spectrum of the aforementioned project facilitating the analysis of other pharmacological properties probably present in the large number of medicinal plants used by people in a traditional way. The sampling of the native medicinal plants will be limited to the area of the Austro Ecuadorian (Azuay, Cañar and Morona Santiago) based on the ethno-medical information reported in the specialized bibliography. A total of 30 plants will be collected, identified in the herbarium of the University of Azuay (HA) and processed according to the standardized work procedures established in the medicinal plants project. Methanol extracts will be obtained from each plant species and analyzed in the biological model of zebra fish. The extracts that show anti-inflammatory activity in the fish will be analyzed in their phytochemical composition through the use of chromatographic techniques such as HPLC (High Pressure Liquid Chromatography), TLC (Thin Layer Chromatography), and column chromatography. From the academic point of view, the project aims to support the institutional transformation promoted at the University of Cuenca and position our institution as a reference entity in the area. From the social point of view, through the described analysis it is intended to obtain scientific information you will see that allows the rational and sustainable use of the biodiversity of our country, while protecting an important cultural heritage that is at risk of disappearance such as traditional medicine.

VIII RESEARCH PROJECT COMPETITION AND III RESEARCH PROGRAM COMPETITION