Prevalence of the genotypes of the human virus papilloma in uterine cervical samples and their relationship with the risk factors in women with active sexual life of the cantons of the province of Azuay. 2013-2015

INTRODUCTION Human papillomavirus (HPV) is the causal agent of uterine cervical cancer and can be identified by the PCR technique. Goals. Determine the prevalence of the genotypes of the papilloma virus of high and low human zeal degree, in cervical samples of women with active sexual life of the 14 cantons of the province of Azuay, using the PCR method and relate to the intraepithelial lesions detected by the cytopathological study of Paps Correlacionar the prevalence of high and low human genotypes with the genotypes of existing vaccines that avoid uterine cancer. Correlation HPV genotypes for pre -malignant and malignant lesions of the cervix with risk factors. Epidemiological, observational, transverse study methodology. Random sample of 500 women with sexual life who live in the 14 cantons of the province of Azuay. The identification of genotypes and cervical lesions will be carried out in uterine cervical samples, in the Molecular Biology Laboratory of the Faculty of Medical Sciences of the University of Cuenca, and cervical lesions by means of a cytopathological study in the pathological anatomy laboratory of the Diagnostic Center of the same faculty. Expected results and products. 1.- The prevalence of the Genotypes of the low and high oncogenic virus virus will be known, which will identify women who have the potential to generate cervical cancer; In addition, cytological characteristics will be identified through the Pap -Louoau technique. 2.- The prevalence of genotypes in relation to age groups will be known. 3.- The degree of efficacy of the two existing vaccines will be inferred. 4.- The relationship of genotypes with risk factors will be known.

XII UNIVERSITY COMPETITION FOR RESEARCH PROJECTS UNIVERSITY OF CUENCA